The Gut-Brain Axis in Foetal-Maternal Relationship

Abstract

Gut-brain axis (GBA) represents a bidirectional communication between the central nervous system (CNS) and gastrointestinal (GI) tract. Microbiota found in GI tract has beneficial relationship with their host and can affect the brain, behavior. Studies performed on animals suggest that any change in the composition of microbiota might cause alternations in behavior. In the same way, changes in behavior such as stress, showed to affect the microbiota. Moreover, the composition of the maternal microbiome in pregnancy is known to adversely influence neonatal and infant health and preterm birth. Mother’s microbiome is inherited from the mother to children.